Low-coherence full-field interferometry of volume structure of crystallised soline solution of protein
Al.L. Kalyanov, V.V. Lychagov, L.I. Malinova, A.A. Paiziev, V.P. Ryabukho

Saratov State University named after N.G.Chernyshevsky,
FGE Saratov SII cardiology Rosmedtechnologii,

Institute of Electronic of Uzbekistan Academy of Sciences

Full text of article: Russian language.

Abstract:
Low-coherence full-field interferometry method is proposed to investigate inner structure of transparent layered biological objects. Visualization program and algorithm of optical and physical property measurements were worked out. It was shown in the paper that this method can be used in volume structure of crystallized drop of biological liquid investigation in static and dynamic process. Microtomograms of fragments of the drops are shown. Methods of contact angle and local refractive index measurements are investigated. Significant differences of local refractive index of different parts of drops are detected. Dynamic of contact angle of drying drop are shown.

Key words:full-filed low coherence interferometry, tomography, interference measurements, visualization, wedge dehydration of protein.

References:

  1. Matunina, S.A. Endothelial cells status modeling using its photos / S.A. Matunina, N.S. Seliverstova // Computers optics. – 2002. – Vol. 24. – P. 173-177.
  2. Kupriyanov, A.V. Diagnostic parameters of eye grounds blood vessels near optic disk estimation / A.V. Kupriyanov, N.Yu. Il'yasova, M.A. Anan'in // Computers optics. – 2006. – Vol. 29. – P. 141-145.
  3. Il'yasova, N.Yu. Method of central lines of blood vessels separation on diagnostic images / N.Yu. Il'yasova, A.O. Korepanov, P.M. Chikulaev // Computers optics. – 2006. – Vol. 29. – P. 146-150.
  4. Gul'kova, E.S. Technique of leukocyte separation on images of blood preparation / E.S. Gul'kova, N.Yu. Il'yasova, A.V. Kupriyanov // Computers optics. – 2007. – Vol. 31, N. 2. – P. 77-81.
  5. Plastinin, A.I. Develop of methods of color and texture characters forming for biomedical images analyzing / A.I. Plastinin, A.V. Kupriyanov, N.Yu. Il'yasova // Computers optics. – 2007. – Vol. 31, N. 2. – P. 82-85.
  6. Shabalin, V.N. Morphology of human biological liquids / V.N. Shabalin, S.N. Shatohina – Moscow, Hrizostom, 2001. – 304 p. – (in Russian).
  7. Rapis, E. A change in the physical state of a nonequilibrium blood plasma protein film in patients with carcinoma / E. Rapis // Technical Physics. – Vol. 47, N. 4. – P. 510–512.
  8. Yakhno, T.A. On the existence of regular structures in liquid human blood serum (plasma) and phase transitions in the course of its drying / T.A. Yakhno, O.A. Sedova, A.G. Sanin, A.S. Pelyushenko // Technical Physics. –2003. – Vol. 48, N. 4. – P. 399–403.
  9. Malinova, L.I. Diagnostic significance of plasma dehydration self-organization of patients with hart ischemia disease / L.I. Malinova, Yu.V. Sergeeva, G.V. Simonenko, T.P. Denisova, P.Ya. Dovgalevskii, V.V. Tuchin // Clinical Laboratory Diagnostic. – 2007. – N. 10. – P. 14-16. – (in Russian).
  10. Fundamental morphology of blood serum of patients with hart ischemia disease / edited by L.I. Malinova, A.A. Svistunov, T.P. Denisova, Yu.V. Sergeeva. – Saratov, Novii Veter, 2008. – 56 p. – (in Russian).
  11. Tarasevich, Yu.Yu. Drying of a multicomponent solution drop on a solid substrate: Qualitative analysis / Yu.Yu. Tarasevich, D.M. Pravoslavnova // Technical Physics. –2007 – Vol. 52, N. 2. – P. 159–163.
  12. Rapis, E.G. Regular structure formation of drying protein film / E.G. Rapis // Technical Physics Letters. – 1988. – Vol. 14, N. 17. – P. 1560–1564. – (in Russian).
  13. Rapis, E.G. Autowave process of protein film phase change / E.G. Rapis // Technical Physics. – 1991. – Vol. 61, N. 4. – P. 62–71. – (in Russian).
  14. Rapis, E. Properties and symmetry of the solid cluster phase of protein / E. Rapis // Technical Physics. – Vol. 46, N. 10. – P. 1307–1313.
  15. Rapis, E. On the problem of nucleation (cell formation) in self-organization of protein nanostructures in vitro and in vivo / E. Rapis // Technical Physics. – Vol. 50, N. 6. – P. 780–786.
  16. Golbraikh, E. On the crack pattern formation in a freely drying protein film / E. Golbraikh, E.G. Rapis and S.S. Moiseev // Technical Physics. – Vol. 48, N. 10. – P. 1333–1337.
  17. Rapis, E. Self-organization and supramolecular chemistry of protein films from the nano-to the macroscale / E. Rapis // Technical Physics. – Vol. 49, N. 4. – P. 494–498.
  18. Rapis, E. Nonequilibrium state of self-organized protein nanostructures / E. Rapis // Technical Physics. – Vol. 51, N. 2. – P. 268–273.
  19. Rapis, E.G. Self-assembly of cluster protein films (allotropic nonequilibrium noncrystalline modification) during the process or their condensation / E.G. Rapis // Technical Physics. – 2000. – Vol. 45, N. 1. – P. 121–131.
  20. Tarasevich, Yu.Yu. Effect of diffusion on the separation of components in a biological fluid upon wedge-shaped dehydration / Yu.Yu. Tarasevich, A.K. Ayupova // Technical Physics. –2003. – Vol. 48, N. 5. – P. 535–540.
  21. Tarasevich, Yu.Yu. Mechanisms and models of the dehydration self-organization in biological fluids / Yu.Yu. Tarasevich // Physics-Uspekhi. – 2004. – Vol. 47, N. 7. – P.717.
  22. Yakhno, T.A. Protein and salt: Spatiotemporal dynamics of events in a drying drop / T. A. Yakhno, V. G. Yakhno, A. G. Sanin, O. A. Sanina and A. S. Pelyushenko // Technical Physics. –2004. – Vol. 49, N. 8. – P. 1055–1063.
  23. Yakhno, T.A. Structural evolution of drying drops of biological fluids / T.A. Yakhno, V.G. Yakhno // Technical Physics. – 2009. –Vol. 54, N. 8. – 1219–1227.
  24. Lychagov, V.V. Low_Coherence Interference Microscopy of the Internal Structure of Crystallized Blood Plasma / V.V. Lychagov, A.L. Kalyanov, V.P. Ryabukho // Optics and Spectroscopy. – 2009. – Vol. 107, N. 6. – P. 859–865.
  25. Dubois, A. High-resolution full-field optical coherence tomography with a Linnik microscope / A. Dubois, L. Vabre, A. Boccara, E. Beaurepaire // Applied Optics. – 2002. – Vol. 41, N. 4. – P. 805–812.
  26. Vabre, L. Thermal-light full-field optical coherence tomography / L. Vabre, A. Dubois, A.C. Boccara // Optics Letters. – 2002. – Vol. 27, N. 7. – P. 530–532.
  27. Laude, B. Full-field coherence tomography with thermal light / Laude B., De Martino A., Dravillon B., Benattar L., Schwartz L. // Applied Optics. – 2002. – Vol. 41, N. 31. – P. 6637–6645.
  28. Vishnyakov, G.N. Tomographic microscopy of three-dimensional phase objects in spatially incoherent light / G.N. Vishnyakov, G.G. Levin, V.L. Minaev // Optics and Spectroscopy. –2003. – Vol. 95, N. 1. – P. 134–138.
  29. Oh, W.Y. Ultrahigh-resolution full-field optical coherence microscopy using InGaAs camera / Oh W.Y., Bouma B.E., Iftimia N., Yun S.H., Yelin R., Tearney G.J. // Optics Express. – 2006. – Vol.14, N. 2. – P. 726–735.
  30. Ohmi, M. Ultra-high resolution optical coherence tomography (OCT) using a halogen lamp as the light source / M. Ohmi, M. Haruna. // Optical Review. – 2003. – Vol. 10, N. 5. – P. 478–481.
  31. Akiba, M. In vivo video-rate cellular-level full-field optical coherence tomography / M. Akiba, Kin Pui Chan. // Journal of biomedical optics. – 2007. – Vol. 12, N. 6. – P. 064024.
  32. Dubois, A. Ultrahigh-Resolution Full-Field Optical Coherence Tomography / A. Dubois, K. Grieve, G. Moneron, R. Lecaque, L. Vabre, C. Boccara // Applied Optics. – 2004. – Vol. 43, N. 14. – P. 2874–2883.
  33. Angelsky, O.V. Optical correlation diagnostics of rough surfaces with large surface inhomogeneities / O.V. Angelsky, A.P. Maksimyak, P.P. Maksimyak, S.G. Hanson // Optics express. – 2006. – V. 14, N. 6. – P. 7299–7311.
  34. Dubois, A. Spectroscopic ultrahigh-resolution full-field optical coherence microscopy / A. Dubois, J. Moreau, C. Boccara // Optics Express. – 2008. – Vol. 16, N. 21. – P. 17082–17091.
  35. Moneron, G. Polarization-sensitive full-field optical coherence tomography / G. Moneron, A.C. Boccara, A. Dubois // Optics letters. – 2007. – Vol. 32, N. 14. – P. 2058-2060.
  36. Lingfeng, Yu Full-color three-dimensional microscopy by wide-field optical coherence tomography / Yu Lingfeng, M.K. Kim // Optics Express. – 2004. – Vol. 12, N. 26. – P. 6632–6641.
  37. Ahmanov, S.A. Introduction in statistic radiophysics and optics / S.A. Ahmanov, Yu.E. D'yakov, A.S. Chirkin – Moscow, Nauka. – 1981. – 640 p.
  38. Goodman, J.W. Statistical optics / J.W. Goodman – John Wiley & Sons, New York, 1985.
  39. Fercher, A. F. Optical coherence tomography - principles and applications / A. F. Fercher, W. Drexler, C. K. Hitzenberger, T. Lasser // Report Prog. Phys. – 2003. – Vol. 66. N. 2.– P. 239–303.
  40. Gurov, I.P. Optical coherence tomography: principles, problems and perspectives / I.P. Gurov // Problems of coherence and nonlinear optics, edited by I.P. Gurov, S.A. Kozlova. – Sent-Petersburg, SPbGU ITMO. – 2004. – P. 6–30. – (in Russian).
  41. Borodin, S.A. Automated device for substrate cleanness estimation using dynamic status of liquid drop on substrate surface / S.A. Borodin, A.V. Volkov, N.L. Kazansky // Computers optics. 2005. – Vol. 28. – P. 69-76.

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